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NOAA Fisheries Northwest Science Center Publication Details

CitationLi-Jung Kuo, Jacob Tietsort, Jennie L. Bolton, Jonelle B. Gates, Mariko Langness, Andrea Carey, Sandra O'Neill, Irvin R. Schultz (2025) Analysis of 6PPD-Q in finfish, shellfish, and marine mammal tissues. Chemosphere, Volume 379, 144418. (https://doi.org/10.1016/j.chemosphere.2025.144418)
TitleAnalysis of 6PPD-Q in Finfish, Shellfish, and Marine Mammal Tissues
Publication Year2025
Volume379
Pages144418
Keywordsshellfish, puget sound, marine mammal., finfish, 6ppd-q
AbstractToxic urban stormwater runoff is known to degrade surface water quality and the aquatic habitats, and thus constraints the conservation and recovery efforts for aquatic species. One example is the severe pre-spawn mortality syndrome in coho salmon (Oncorhynchus kisutch) in the Pacific Northwest of the United States. Recent discoveries identified 6PPD-quinone (6PPD-Q), a transformation product of tire rubber anti-oxidant 6PPD [N-(1,3-dimethylbutyl)-N¿-phenyl-para-phenylenediamine], as the causal component. Further toxicity testing revealed that several other fish species are also vulnerable to 6PPD-Q. Environmental monitoring efforts on 6PPD-Q have been focused on water, atmospheric particulate matter, soils, and sediments. Biomonitoring of 6PPD-Q in the tissues is still very scarce. This study presents a workflow for extraction and quantitative analysis of 6PPD-Q in complex tissues from shellfish, finfish, and marine mammals. A multi-residue extraction protocol was developed for
Official CitationLi-Jung Kuo, Jacob Tietsort, Jennie L. Bolton, Jonelle B. Gates, Mariko Langness, Andrea Carey, Sandra O'Neill, Irvin R. Schultz (2025) Analysis of 6PPD-Q in finfish, shellfish, and marine mammal tissues. Chemosphere, Volume 379, 144418.
Links (https://doi.org/10.1016/j.chemosphere.2025.144418)